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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Alcohol. 2010 Feb;44(1):99–110. doi: 10.1016/j.alcohol.2009.09.036

Figure 1.

Figure 1

Effects of acute challenge with 0, 0.75, 1.0, 1.25, and 1.5 g/kg ethanol on social investigation (top) and social preference/avoidance (bottom) of adolescent rats left non-manipulated or repeatedly exposed to saline or 1 g/kg ethanol for 7 days prior to the social interaction test. Data are collapsed across sex (n=10 per group). Asterisks (*) indicate significant acute ethanol-induced changes relative to corresponding controls acutely challenged with saline (0 g/kg) within each pretest condition (p < 0.05) for social investigation and significant ethanol-induced changes relative to saline controls on data collapsed across pre-test condition for social preference/avoidance. # - significant changes in chronically saline- or ethanol-exposed animals relative to non-manipulated controls when challenged with saline on test day (p < 0.05).