Table I.
GnT-IV Activity (pmol/hr mg)
| Mgat4a/Mgat4b | |||
|---|---|---|---|
| Wild type | Mgat4b Null | double Null | |
| Brain | 47.30 ± 4.92 | 60.45 ± 10.45 | N.D. |
| Thymus | 82.45 ± 6.34 | 86.66 ± 1.73 | N.D. |
| Lung | 68.78 ± 3.74 | 51.96 ± 6.91 | N.D. |
| Heart | 18.30 ± 1.37 | 11.83 ± 1.14* | N.D. |
| Liver | 16.34 ± 1.21 | 11.88 ± 1.58 | N.D. |
| Pancreas | 214.73 ± 77.42 | 258.64 ± 48.69 | N.D. |
| Spleen | 116.15 ± 15.91 | 95.38 ± 10.99 | N.D. |
| Stomach | 142.50 ± 47.41 | 91.40 ± 21.11 | N.D. |
| Small intestine | 404.78 ± 228.44 | 463.40 ± 365.60 | N.D. |
| Kidney | 58.03 ± 3.54 | 52.11 ± 2.42 | N.D. |
| Adrenal gland | 22.76 ± 5.55 | 18.57 ± 2.91 | N.D. |
| Colon | 917.16 ± 33.98 | 937.53 ± 185.05 | N.D. |
| Testis | 61.11 ± 5.45 | 36.57 ± 4.43* | N.D. |
| Ovary | 33.52 ± 4.76 | 16.22 ± 0.16* | N.D. |
| Uterus | 80.51 ± 5.87 | 75.72 ± 6.01 | N.D. |
| Lymph nodes | 83.56 ± 9.34 | 84.00 ± 7.54 | N.D. |
| Bone marrow | 23.97 ± 2.23 | 16.39 ± 2.40 | N.D. |
| Muscle | 3.83 ± 0.25 | 2.91 ± 0.38 | N.D. |
Each result represented the mean ± SEM of four independent experiments.
*P < 0.05 versus Wt (unpaired Student's t-test).
N.D.: not detected.