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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: J Immunol. 2009 Nov 30;184(1):296–302. doi: 10.4049/jimmunol.0900604

Figure 4. Caveolin-1 deficiency inhibits the ability of neutrophils to phagocytose P. aeruginosa.

Figure 4

PMN derived from cav1 KO and WT mice were exposed to P. aeruginosa for 180 min to allow for the phagocytosis to occur. PMNs were lysed and aliquots were plated to determine the number of ingested bacteria (A). The phagocytic index represents the number of ingested bacteria per 1 × 106 PMNs. The number of extracellular bacteria was determined by plating and aliquot from the phagocytic reaction on P. aeruginosa selective media without lysing the PMNs. Bars represent means and error bars the SD from a representative experiment. P values determined by a Student T test.