Table IV.
Treatment | Putrescine (pmols/mg protein) |
Spermidine (pmols/mg protein) |
Spermine (pmols/mg protein) |
---|---|---|---|
Control | 2,151±537 | 28,269±1,187 | 20,347±703 |
Pd-spermine | 714±401 | 17,606±1,359 | 14,673±1,344 |
Pt-spermine | 2,479±627 | 33,379±6,142 | 25,838±4,948 |
A2780 cells were treated with Pd-spermine or Pt-Spermine (10 μM ) for 20 h followed by 24 h in drug free medium. The cells were harvested thereafter and assayed for polyamine pools. Untreated cells were used as controls. Data are an average of 3 measurements.