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. 2010 Jun;21(6):966–973. doi: 10.1681/ASN.2009080872

Figure 5.

Figure 5.

More robust activation of the RAS in VDR-null mice under UUO. (A) Immunostaining of sham-operated and obstructed kidney sections with AngI/II-specific antibody. (B) Semiquantitative score of the AngI/II immunostaining of the kidney sections. (C) Northern blot analysis of renin expression in these kidneys. (D) Real-time RT-PCR analysis of the components of the RAS in the sham-operated and obstructed kidneys from VDR(+/+) and VDR(−/−) mice. Renin R, (pro)renin receptor; ACE, angiotensin-converting enzyme. *P < 0.05, **P < 0.01, ***P < 0.001 versus sham of the same genotype; #P < 0.05, ##P < 0.01, ###P < 0.001 versus corresponding VDR(+/+) (sham or UUO).