Table 2.
Studies of Dose Accuracy of Insulin Pens with Comparable End Points
| Original FlexPena | Improved FlexPen | HumaPen LUXURA | SoloSTAR | OptiClik | Reference | |
|---|---|---|---|---|---|---|
| Deviation from 10-IU dose (mean) | 1.64 ± 0.84% | NAb | 1.10 ± 0.20% | 2.61 ± 0.92% | 4.78 ± 3.31% | 59 |
| NA | 1.63 ± 0.84%c | NA | 2.11 ± 0.92% | NA | 64 | |
| Deviation from 30-IU dose (mean) | 0.83 ± 0.26% | NA | 0.62 ± 0.19% | 1.70 ± 0.84% | 2.97 ± 2.48% | 59 |
| NA | 1.23 ± 0.76%d | NA | 1.54 ± 0.84% | NA | 64 | |
| Mean delivered dose of 5 IU | 5.07 ± 0.15 | NA | NA | 5.03 ± 0.21 | NA | 61 |
| 4.95 ± 0.19 | NA | NA | 4.86 ± 0.39 | NA | 62 | |
| Mean delivered dose of 10 IU | 9.87 ± 0.16 | NA | NA | 9.83 ± 0.14 | NA | 61 |
| 9.61 ± 0.27 | NA | NA | 9.27 ± 0.52 | NA | 62 | |
| Mean delivered dose of 30 IU | 29.70 ± 0.38 | NA | NA | 29.45 ± 0.25 | NA | 61 |
| 29.70 ± 0.34 | NA | NA | 28.73 ± 0.47 | NA | 62 |
a
No longer available commercially.
b
Not assessed.
c
p < 0.001
d
p < 0.05 for improved FlexPen vs SoloSTAR.