Table 1.
Clinical and Biochemical Characteristics of Study Population (Mean ± Standard Deviation)
| Female (n = 438) | Male (n = 300) | |||
|---|---|---|---|---|
| NGT (n = 319) | IGT (n = 119) | NGT (n = 252) | IGT (n = 48) | |
| Age (years) | 43 ± 12 | 49 ± 9a | 42 ± 13 | 53 ± 11a |
| BMI (kg/m2) | 24.7 ± 5.2 | 26.2 ± 4.5a | 23.2 ± 4.2 | 24.5 ± 3.5 |
| Waist circumference (cm) | 84.5 ± 12.3 | 90.6 ± 11.3a | 86.3 ± 11.7 | 93.0 ± 9.9a |
| Smoking (n, %) | 0 | 0 | 102 (40.5%) | 13 (27.1%) |
| Drinking (n, %) | 3 | 1 | 115 (45.6%) | 15 (31.3%) |
| Systolic blood pressure (mm Hg) | 120 ± 18 | 131 ± 21a | 118 ± 15 | 128 ± 17a |
| Diastolic blood pressure (mm Hg) | 74 ± 10 | 80 ± 12a | 75 ± 11 | 79 ± 10a |
| Log HOMA-IR | 0.18 ± 0.28 | 0.41 ± 0.28a | 0.13 ± 0.27 | 0.35 ± 0.25a |
| Log fasting insulin | 0.86 ± 0.28 | 1.04 ± 0.29a | 0.81 ± 0.26 | 0.97 ± 0.26a |
| HbA1c | 5.66 ± 0.51 | 6.10 ± 0.62a | 5.61 ± 0.52 | 6.21 ± 0.59 |
| Total cholesterol (mg/dl) | 186 ± 38 | 200 ± 35a | 178 ± 36 | 189 ± 36 |
| Log triglyceride | 2.00 ± 0.20 | 2.09 ± 0.17a | 2.04 ± 0.21 | 2.15 ± 0.21a |
| LDL cholesterol (mg/dl) | 117 ± 32 | 129 ± 31a | 112 ± 32 | 116 ± 33 |
| HDL cholesterol (mg/dl) | 46.6 ± 9.8 | 44.7 ± 9.7 | 41.0 ± 9.5 | 41.1 ± 9.4 |
| Log adiponectin | 0.89 ± 0.25 | 0.87 ± 0.16 | 0.82 ± 0.24 | 0.82 ± 0.13 |
| hsCRP (mg/liter)b | 3.0 ± 3.1 | 4.0 ± 2.6a | 1.94 ± 2.3 | 2.46 ± 2.1 |
a
The mean value was significantly different from NGT subjects analyzed by student t tests.
b
The hsCRP was determined in a subgroup of subjects (n = 94 and 98 in female NGT and IGT, respectively; n = 64 and 37 in males NGT and IGT, respectively).