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. 2010 Jun 2;4:18. doi: 10.3389/fncel.2010.00018

Figure 5.

Figure 5

IPSCs in CA1 pyramidal cells of NOD and Balb mice differ in τ decay times. (A) Hippocampal slice (top) placed on a 64 electrode grid and example traces of local field potential and corresponding IPSCs in a CA1 pyramidal cell from an NOD mouse. Histogram (bottom) of decay time constants of IPSCs from NOD and Balbc mice. Histograms are fitted with lognormal functions. (B) Decay time constants of NOD (n = 11) and Balbc (n = 7) mice. NOD mice have faster decay time constants than Balbc mice (p < 0.05). (C) IPSC frequencies of NOD and Balbc mice. (D) (top) Average waveform of the field oscillation next to the recording site of the CA1 pyramidal cell. (middle) IPSC event probability histogram at different phases of the oscilation. (bottom) EPSC event probability histogram at different phases of the oscilation from an NOD mouse. Average values + SEM are shown in black.