Rana catesbeiana tadpole. (A) Kidney showing lesions produced by Ranavirus. Complete loss of normal architecture. Cell necrosis with pyknosis and karyorrhexis (arrowheads), mononuclear lymphocyte infiltrate (white arrow), and eosinophilic infiltration (black arrows). H&E stain. Scale bar = 100 μm, (B) Liver with lesions produced by Ranavirus. Diffuse necrosis with pyknosis and karyorrhexis, areas of steatosis, vacuolized hepotocytes with loss of trabecular structure, and mononuclear infiltrate. Arrowheads indicate normal hepatocytes. H&E stain. Scale bar = 50 μm