Table 4. Effect estimates for terminal density from the result of Design Expert analysis.

Coded coefficients are transformed so the high value of the factor becomes +1 and the low value becomes −1 (i.e. for A, 50μm becomes +1 and 10 μm becomes −1).

	Factor	Coefficient (Actual Factor)	Coefficient (Coded Factor)	Standard Error (Coded)	Percent Contribution	P-value
A7	Model					<0.0001*
	Intercept	−41900	49700	1430
	B-stripe width	538	6880	2060	4.7%	0.0011*
	C-plating density	0.698	20200	1680	61.1%	<0.0001*
	D-culture time	1620	11200	1380	28.3%	<0.0001*
	BC	0.0189	6030	2380	2.7%	0.0127*
	BD	−22.7	−5450	1980	3.2%	0.0068*
	Lack of fit					0.1557**
HUVEC	Model					<0.0001*
	Intercept	−1960	28000	811
	C-plating density	0.445	7120	951	57.7	<0.0001*
	D-culture time	424	5090	795	42.3	<0.0001*
	Lack of fit					0.9799**
SC	Model					<0.0001*
	Intercept	1330	53300	1030
	A-space width	248	−5930	1480	6.4%	0.0001*
	B-stripe width	−666	7580	1490	10.3%	<0.0001*
	C-plating density	1.43	15000	1230	59.3%	<0.0001*
	D-culture time	38.7	6730	1020	17.3%	<0.0001*
	AC	−0.0165	−5280	1790	3.5%	0.004*
	BD	17.4	4180	1480	3.2%	0.0057*
	Lack of fit					0.1925**

^*indicates the factor as a significant contributor to the model with p<0.05,

^**indicates an insignificant lack of fit with p>0.05