Schematic drawing of the eye and histology of a rodent retina. The retina consists of multiple well-defined layers.1-3 Starting from the vitreous boundary, they include the ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), and photoreceptor inner (IS) and outer segments (OS). The retina is nourished by two separate blood supplies, the retinal and choroidal circulations. The retinal vessels are within the GCL, INL, IPL, and OPL. The choroidal vessels are located posterior to the photoreceptor layer. The outer nuclear layer and the inner and outer segments are avascular. Adapted from Fig. 1 of Shen et al., J Magn Reson Imaging.48