Table 4.
Backbone-backbone NOEs of disulfide-cyclized TATE, previously synthesized [14], beta-sheet and distorted helical conformations
| beta-sheet | distorted helical | ||||
|---|---|---|---|---|---|
| NOE | I | d | NOE | I | d |
| Phe1 αH-Cys2 HN | S | 1.8–2.7 Å | Lys5 αH-Thr8 HN | W | 1.8–6.0 Å |
| Cys2 αH-Tyr3 HN | M | 1.8–3.5 Å | Thr6 HN-Thr8 HN | W | 1.8–6.0 Å |
| Thr6 αH-Cys7 HN | S | 1.8–2.7 Å | Thr6 αH-Thr8 HN | W | 1.8–6.0 Å |
| Thr6 NH-Cys7 HN | M | 1.8–3.5 Å | Thr6 HN-Cys7 HN | M | 1.8–3.5 Å |
| Cys2 αH-Cys7 HN | M | 1.8–3.5 Å | Cys7 HN-Thr8 HN | M | 1.8–3.5 Å |
| Cys2 NH-Cys7 HN | M | 1.8–3.5 Å | Lys5 αH-Thr6 HN | W | 1.8–6.0 Å |
| Thr6 αH-Cys7 HN | S | 1.8–2.7 Å | |||
| Cys7 αH-Thr8 HN | M | 1.8–3.5 Å | |||
The strength of cross peak signal intensities (I) are presented as strong (S), medium (M), and weak (W). The distance (d) is listed as lower limit to upper limit.