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The putative changes in the renal transport system in the elderly are shown. In animal studies there is a decrease in the abundance of AQP2, AQP3, NKCC2/BSC1 and UT-A1, A2, A3. The arrrows represent the transporters and water channels known to be downregulated in animal studies. These changes may be present in the elderly population affecting the diluting and concentrating capacity.
