Table 1.
The sepsis-related organ failure assessment (SOFA) score evaluation system of multiple organ dysfunction [12]. Six organ systems are evaluated as a scale of 1-4 each. The arithmetical sum of these six is the value of the SOFA score.
| Score points | 1 | 2 | 3 | 4 |
| Respiration | ||||
| PaO2/FiO2 | < 400 | < 300 | < 200 | < 100 |
| with respiratory support | with respiratory support | |||
| Coagulation | ||||
| Platelets ×103/mm3 | < 150 | < 100 | < 50 | < 25 |
| Liver | ||||
| Bilirubin mg/dl | 1.2–1.9 | 2.0–5.9 | 6.0–11.9 | > 12.0 |
| Cardiovascular | ||||
| Hypotensiona | MAP < 70mmhg | Dopamine ≤ 5 or | Dopamine > 5 or | Dopamine > 15 or |
| dobutamine in any dose | epinephrine ≤ 0.1 or | epinephrine > 0.1 or | ||
| norepinephrine ≤ 0.1 | norepinephrine > 0.1 | |||
| Central nervous system | ||||
| Glasgow Coma Scale | 13–14 | 10–12 | 6–9 | < 6 |
| Renal | ||||
| Creatinine mg/dl | 1.2–1.9 | 2.0–3.4 | 3.5–4.9 | 5.0 |
| or urine output | or < 500ml/24h | or < 200ml/24h |
aAdrenergic agents administered for at least 1 h (doses are given in μ g/kg/min). MAP, mean arterial pressure.