Figure 4. Src kinases inhibition does not affect expression of IL-23A and cREL.

MoDC were pretreated or not with PP2 (20 µM) and stimulated with PolyI∶C (20 µg/ml) or R848 (10 µM) for 4 hours. qRT-PCR was performed to analyze expression of cytokine genes (A) or transcription factor genes (B). Fold induction for the expression of each gene compared to unstimulated cells is plotted. Expression levels for each analyzed gene were normalized to β-Actin. Three or four independent experiments and the p values for the differences between the groups are shown (p value <0.05 is significant).