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. 2010 Jul 9;5(7):e11493. doi: 10.1371/journal.pone.0011493

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Jugessur et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The QQ plots compare the distribution of the observed Fisher-combined p-values (-log₁₀ scale) for both populations with an expected uniform distribution under the null (sloping line). The plots for the Norwegian control-parent triads, iCL/P triads, and iCP triads are provided separately for TRIMM in A, C and E respectively (left-hand side of the plot). The corresponding plots for HAPLIN are provided in B, D and F respectively (right-hand side of the plot). Gene labels for the top six most significant genes are displayed in each plot. Shaded areas represent 95% confidence interval bands and dotted lines indicate the expected ranked p-value of 0.05.