Table 5. Mammalian gene set enrichment analysis results.

Gene Set	Enriched at 24H	24H P-Value	24H FDR	Enriched at 48H	48H P-Value	48H FDR	Enriched at 72H	72H P-Value	72H FDR
TGAATGT,MIR-181A,MIR-181B,MIR-181C,MIR-181D	Forskolin	0.475	1	Forskolin	0.001	0.009	Control	<0.001	0.001
ACTGTGA,MIR-27A,MIR-27B	Forskolin	0.238	1	Forskolin	0.406	1	Control	0.002	0.042
CAGTGTT,MIR-141,MIR-200A	Control	0.683	1	Forskolin	0.017	0.648	Control	0.002	0.031
V$E2F_Q6	Forskolin	0.033	0.273	Forskolin	0.001	0.015	Forskolin	0.004	0.035
V$E2F1_Q6	Forskolin	0.003	0.009	Forskolin	0.003	0.102	Forskolin	<0.001	0.034
V$E2F_Q4	Forskolin	0.014	0.064	Forskolin	0.002	0.056	Forskolin	0.008	0.064
V$E2F_Q4_01	Forskolin	0.014	0.064	Forskolin	0.001	0.003	Forskolin	0.019	0.121
V$E2F1_Q3	Forskolin	0.126	0.994	Forskolin	0.014	0.53	Forskolin	0.006	0.121
SGCGSSAAA_V$E2F1DP2_01	Forskolin	0.056	0.733	Forskolin	0.008	0.301	Forskolin	0.014	0.121
V$E2F1DP2_01	Forskolin	0.055	0.549	Forskolin	0.001	0.016	Forskolin	0.031	0.14
V$E2F1_Q4_01	Forskolin	0.254	1	Forskolin	0.001	0.016	Forskolin	0.016	0.142
V$E2F4DP1_01	Forskolin	0.055	0.677	Forskolin	0.002	0.062	Forskolin	0.016	0.137
V$E2F_02	Forskolin	0.056	0.601	Forskolin	0.001	0.016	Forskolin	0.016	0.132
V$E2F1DP1RB_01	Forskolin	0.033	0.35	Forskolin	0.001	0.003	Forskolin	0.02	0.14
V$E2F1DP1_01	Forskolin	0.055	0.771	Forskolin	0.001	0.018	Forskolin	0.024	0.139
V$E2F1_Q6_01	Forskolin	0.003	0.009	Forskolin	0.007	0.256	Forskolin	0.073	0.224
V$E2F_Q3	Forskolin	0.194	1	Forskolin	0.002	0.069	Forskolin	0.068	0.227

Shown are the mammalian gene set enrichment analysis results for selected gene sets of interest at 24, 48, and 72 hours. Italicized are those gene sets with p-value <0.05 and false discovery rate (FDR) <0.25, which are taken as significant. Gene sets are directly as they appear in the Molecular Signatures Database on the Broad Institute website.