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. Author manuscript; available in PMC: 2011 Jul 9.
Published in final edited form as: Circ Res. 2010 May 6;107(1):106–116. doi: 10.1161/CIRCRESAHA.109.214601

Table 2.

Mitochondrial H2O2 and respiration in AngII-stimulated BAEC treated with mitoTEMPO.

H2O2, pmol/mg/min Respiration, nmol/mg/min
Malate +
Glutamate		 Succinate Malate + Glutamate Succinate
State 3 Sate 4 RCR State 3 State 4 RCR
Control 67±4 234±20 11.6±0.7 3.3±0.4 3.5±0.1 9.5±0.3 4.7±0.6 2.0±0.4
mitoTEMPO 72±5 235 ±19 11.5±0.6 3.2±0.5 3.6±0.4 9.3±0.4 4.5±0.7 2.1±0.4
Ang II * 133 ±12 377±30 8.2±0.5 5.3±1.0 1.5±0.6 7.9±0.2 6.9±0.5 1.1±0.3
Ang II+mitoTEMPO§ 79±4 227±24 9.8±0.7 3.7±0.5 2.7±0.5 9.1±0.3 4.8±0.6 1.9±0.3

Results are mean ± SEM. Ang II = angiotensin II.

*

P < 0.05 vs control,

§

P < 0.05 vs AngII.