Table 2.
Multivariate hazard ratios (HR) and 95% confidence intervals (CI) according to quintile of meat or fruit and vegetable intake and glioma risk
| Meat or fruit and vegetable intake | Quintile of intake |
||||||
|---|---|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | Q5 | p-trend | p-sex interaction | |
| Processed meat | |||||||
| Median Intake* | 0.08 | 0.17 | 0.28 | 0.43 | 0.78 | ||
| Number of cases | 99 | 133 | 125 | 106 | 122 | ||
| Multivariate HR† | 1.00 | 1.26 | 1.14 | 0.94 | 1.05 | 0.44 | 0.24 |
| 95% CI | (ref) | 0.97–1.64 | 0.88–1.49 | 0.71–1.24 | 0.80–1.37 | ||
| Red meat | |||||||
| Median intake* | 0.31 | 0.66 | 0.97 | 1.33 | 1.94 | ||
| Number of cases | 114 | 117 | 131 | 113 | 110 | ||
| Multivariate HR† | 1.00 | 0.98 | 1.06 | 0.89 | 0.85 | 0.15 | 0.21 |
| 95% CI | (ref) | 0.76–1.27 | 0.82–1.37 | 0.68–1.16 | 0.65–1.11 | ||
| Fruit and vegetables | |||||||
| Median intake‡ | 1.12 | 1.69 | 2.17 | 2.75 | 3.81 | ||
| Number of cases | 98 | 108 | 132 | 122 | 125 | ||
| Multivariate HR† | 1.00 | 1.09 | 1.36 | 1.30 | 1.42 | 0.0081 | 0.46 |
| 95% CI | (ref) | 0.83–1.44 | 1.05–1.77 | 0.99–1.71 | 1.08–1.86 | ||
| Fruit | |||||||
| Median intake‡ | 0.30 | 0.67 | 1.01 | 1.44 | 2.26 | ||
| Number of cases | 108 | 105 | 127 | 126 | 119 | ||
| Multivariate HR† | 1.00 | 0.96 | 1.17 | 1.18 | 1.16 | 0.14 | 0.12 |
| 95% CI | (ref) | 0.73–1.26 | 0.90–1.52 | 0.91–1.53 | 0.89–1.52 | ||
| Whole fruit | |||||||
| Median intake‡ | 0.14 | 0.36 | 0.60 | 0.91 | 1.52 | ||
| Number of cases | 108 | 104 | 111 | 127 | 135 | ||
| Multivariate HR† | 1.00 | 0.95 | 1.03 | 1.21 | 1.34 | 0.0037 | 0.025 |
| 95% CI | (ref) | 0.73–1.25 | 0.79–1.35 | 0.93–1.57 | 1.04–1.75 | ||
| Whole fruit (males) | |||||||
| Number of cases | 79 | 74 | 85 | 89 | 92 | ||
| Multivariate HR† | 1.00 | 0.97 | 1.19 | 1.39 | 1.70 | <0.0001 | |
| 95% CI | (ref) | 0.71–1.33 | 0.87–1.62 | 1.02–1.88 | 1.25–2.31 | ||
| Whole fruit (females) | |||||||
| Number of cases | 29 | 30 | 26 | 38 | 43 | ||
| Multivariate HR† | 1.00 | 0.87 | 0.65 | 0.80 | 0.75 | 0.39 | |
| 95% CI | (ref) | 0.52–1.46 | 0.38–1.10 | 0.49–1.30 | 0.47–1.21 | ||
| Fruit juices | |||||||
| Median intake‡ | 0.02 | 0.11 | 0.30 | 0.52 | 1.01 | ||
| Number of cases | 118 | 107 | 124 | 125 | 111 | ||
| Multivariate HR† | 1.00 | 0.90 | 1.03 | 1.02 | 0.94 | 0.90 | 0.98 |
| 95% CI | (ref) | 0.69–1.17 | 0.80–1.32 | 0.80–1.32 | 0.72–1.22 | ||
| Vegetables | |||||||
| Median intake‡ | 0.55 | 0.82 | 1.06 | 1.34 | 1.92 | ||
| Number of cases | 104 | 112 | 118 | 139 | 112 | ||
| Multivariate HR† | 1.00 | 1.06 | 1.13 | 1.37 | 1.17 | 0.11 | 0.99 |
| 95% CI | (ref) | 0.81–1.39 | 0.87–1.48 | 1.06–1.77 | 0.89–1.53 | ||
*
MPED ounce equivalents/1,000 kcal per day.
†
Adjusted for sex, age (continuous), race (non-Hispanic White, non-Hispanic Black, other, and missing), energy intake (continuous), education (<high school, high school graduate, post-high school other than college, some college, college graduate, postgraduate, and missing), height (8 pre-specified categories and missing), and history of cancer at baseline (yes, no, and missing).
‡
MPED cup equivalents/1,000 kcal per day.