Table 1.
Included studies on the risk of subsequent cancers in individuals with a personal history of NMSC compared to those with no prior history of NMSC
| First Author | Year | Location | Study Type | Study Years |
# NMSC cases |
# subsequent cancers |
Mean follow up for cases (years) |
Adjustments |
|---|---|---|---|---|---|---|---|---|
| Bower | 2000 | United Kingdom |
Registry-based (South and West) |
1981-1995 | 13961 | 789 | 8.45 | Cancer site, age |
| Cantwell | 2009 | Ireland | Registry-based (Northern Ireland) |
1993-2002 | 20843 | 1377 | not reported | age, 5-year period, sex |
| Chen | 2008 | Maryland | Cohort with individual-level data (CLUE II) |
1989-2005 | 769 | 181 | 8.02 | age, sex, BMI, smoking, education |
| Crocetti | 2001 | Italy | Registry-based | 1976-1995 | 198303 | 6974 | 2.57 | Cancer site, age, sex, registry, 5-year period |
| de Vries | 2007 | Netherlands | Registry-based (Eindhoven) |
1972-2002 | 12078 | 253 (prostate) | 5.0 SCC, 5.6 BCC | age, 5-year period |
| Efird | 2002 | California | Cohort with individual-level data (Kaiser Permanente) |
1974-1995 | 822 | 144 | 7.80 | education, BMI (alcohol, smoking, occupational exposure, marital status did not change model) |
| Friedman | 2000 | California | Cohort with individual-level data (Kaiser Permanente) |
1974-1997 | 3164 | 556 | 11.30 | matched on sex, zip code, skin color, age ± 2, date joined. Multivariate: age at dx, parent hx cancer, marital status, education, smoking, alcohol, occupational exposure, BMI, parity, age at menarche and menopause |
| Frisch | 1995 | Denmark | Registry-based | 1978-1989 | 5132 | 815 | 4.47 | Cancer site, age, sex |
| Frisch | 1996 | Denmark | Registry-based | 1978-1991 | 37674 | 3663 | 5.07 | Cancer site, age, sex, calendar period |
| Hemminki | 2000 | Sweden | Registry-based (Sweden) |
1958-1996 | 17673 | 3624 | not reported | Age, sex, calendar period |
| Hemminki | 2001 | Sweden | Registry-based (Sweden) |
1958-1996 | 17280 | 192 (HPV- related cancers) |
not reported | Age, sex, calendar period |
| Hemminki | 2003 | Sweden | Registry-based (Sweden) |
1958-1998 | Not reported | 120 (non- Hodgkin) |
not reported | Age, sex, calendar period |
| Jaeger | 1999 | Denmark | Registry-based | 1978-1993 | 1147 | 201 | 5.63 | sex, age, period, cancer site |
| Levi | 1997 | Switzerland | Registry-based (Vaud, Neuchatel) |
1974-1994 | 4639 | 729 | 4.99 | Cancer site, age, calendar period |
| Levi | 1998 | Switzerland | Registry-based (Vaud, Neuchatel) |
1974-1994 | 11878 | 1543 | 6.44 | Cancer site, sex, age, calendar period |
| Levi | 2008 | Switzerland | Registry-based (Vaud, Neuchatel) |
1974-2005 | 28031 | 1517 (prostate, breast, colorectal) |
not reported | Cancer site, sex, age, calendar period |
| Lindelof | 1991 | Sweden | Registry-based (Sweden) |
1971-1983 | 1973 | 236 | 6.5 | sex, cancer site |
| Maitra | 2005 | England | Registry-based (Thames) |
1961-2000 | 25731 | 3359 | not reported | Cancer site, age, sex |
| Milan | 2000 | Finland | Registry-based (Finland) |
1953-1995 | 71924 | 11042 | 8.69 | Cancer site, age ,sex, period |
| Nugent | 2005 | Manitoba | Registry-based (Manitoba) |
1956-2000 | 36789 | 5935 | 9.36 | Cancer site, age ,sex |
| Soerjomataram | 2008 | Netherlands | Registry-based (Eindhoven) |
1972-2002 | 23408 | 463 (breast and colorectal) |
5.65 | Cancer site, age, sex, stage, duration of follow up |