Skip to main content
. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: J Thorac Cardiovasc Surg. 2010 Mar 9;140(3):653–659. doi: 10.1016/j.jtcvs.2009.12.033

Table 1.

List of genes assayed in normal and TAA fibroblasts by QPCR.

Target Gene Symbol UniGene RefSeq Description
MMPs/TIMPs 1 Mmp2 Mm.29564 NM_008610 Matrix metallopeptidase 2
2 Mmp3 Mm.4993 NM_010809 Matrix metallopeptidase 3
3 Mmp7 Mm.4825 NM_010810 Matrix metallopeptidase 7
4 Mmp8 Mm.16415 NM_008611 Matrix metallopeptidase 8
5 Mmp9 Mm.4406 NM_013599 Matrix metallopeptidase 9
6 Mmp11 Mm.4561 NM_008606 Matrix metallopeptidase 11
7 Mmp12 Mm.2055 NM_008605 Matrix metallopeptidase 12
8 Mmp13 Mm.5022 NM_008607 Matrix metallopeptidase 13
9 Mmp14 Mm.280175 NM_008608 Matrix metallopeptidase 14, (MT1-MMP)
10 Mmp15 Mm.217116 NM_008609 Matrix metallopeptidase 15, (MT2-MMP)
11 Timp1 Mm.8245 NM_011593 Tissue inhibitor of metalloproteinase 1
12 Timp2 Mm.206505 NM_011594 Tissue inhibitor of metalloproteinase 2
13 Timp3 Mm.4871 NM_011595 Tissue inhibitor of metalloproteinase 3
14 Timp4 Mm.255607 NM_080639 Tissue inhibitor of metalloproteinase 4
ECM Proteins 15 Col1a1 Mm.277735 NM_007742 Procollagen, type I, alpha 1
16 Col1a2 Mm.277792 NM_007743 Procollagen, type I, alpha 2
17 Col3a1 Mm.249555 NM_009930 Procollagen, type III, alpha 1
18 Col4a1 Mm.738 NM_009931 Procollagen, type IV, alpha 1
19 Col6a1 Mm.2509 NM_009933 Procollagen, type VI, alpha 1
20 Eln Mm.275320 NM_007925 Elastin
21 Ltbp1 Mm.269747 NM_019919 Latent transforming growth factor-beta binding protein 1
22 Ltbp2 Mm.3900 NM_013589 Latent transforming growth factor beta binding protein 2
23 Fbn1 Mm.271644 NM_007993 Fibrillin 1
24 Lamb1-1 Mm.172674 NM_008482 Laminin B1 subunit 1
25 Lamb2 Mm.425599 NM_008483 Laminin, beta 2
26 Lamb3 Mm.435441 NM_008484 Laminin, beta 3
27 Fn1 Mm.193099 NM_010233 Fibronectin 1
28 Spp1 Mm.288474 NM_009263 Secreted phosphoprotein 1, (Osteopontin)
29 Thbs1 Mm.4159 NM_011580 Thrombospondin 1
30 Sparc Mm.291442 NM_009242 Secreted acidic cysteine rich glycoprotein, (SPARC)
31 Ager Mm.3383 NM_007425 Advanced glycosylation end product receptor, (RAGE)
Transcription Factors 32 Sp1 Mm.4618 NM_013672 Trans-acting transcription factor 1, (Sp1)
33 Sp3 Mm.124328 NM_011450 Trans-acting transcription factor 3, (Sp3)
34 Jun Mm.275071 NM_010591 Jun oncogene, (Jun)
35 Junb Mm.1167 NM_008416 Jun-B oncogene, (Jun b)
36 Fos Mm.246513 NM_010234 FBJ osteosarcoma oncogene, (Fos)
37 Fosb Mm.248335 NM_008036 FBJ osteosarcoma oncogene B, (Fos b)
38 Etv4 Mm.5025 NM_008815 Ets variant gene 4 (E1A enhancer binding protein), (PEA-3)
House-keeping Genes 39 Gusb Mm.3317 NM_010368 Glucuronidase, beta
40 Hprt1 Mm.299381 NM_013556 Hypoxanthine guanine phosphoribosyl transferase 1
41 Hspb1 Mm.13849 NM_013560 Heat shock protein 1, (Hsp27)
42 Gapdh Mm.343110 NM_008084 Glyceraldehyde-3-phosphate dehydrogenase

Data compiled using Rebhan et al.(27)