Table 1.

NMR Spectroscopic Data for Fijiolide A (1) (DMSO-d₆)^a

No.	δC, mult. b	δH (J in Hz)	COSY	HMBCc
1	148.8, C
2	135.7, C
3	126.7, C
4	139.3, C
5	129.1, CH	6.64, d (8.0)	6	3, 4, 6, 7, 13
6	125.3, CH	7.08, d (8.0)	5	2, 4, 5, 7, 8
7	147.7, C
8	83.2, CH	5.87, s		1, 2, 6, 7, 9, 10, 21
9	99.8, C
10	135.5, CH	6.62, d (5.3)	11	1, 8, 9, 11, 12
11	138.0, CH	6.65, dd (5.3, 2.1)	10, 12	1, 9, 10, 12,
12	129.4, CH	6.76, d (2.1)	11	1, 2, 9, 10, 11
13	73.1, CH	4.66, dd (11.0, 4.0)	14, 13-OH	3, 4, 5, 14
14	65.9, CH2	4.23, dd (11.0, 4.0), 3.64, dd (11.0, 4.0)	13	4, 13, 15
15	170.0, C
16	42.9, CH2	2.57, dd (13.4, 3.8), 2.07, t (13.4)	17	15, 17, 18
17	49.0, CH	4.61, ddd (13.4, 13.4, 3.8)	16, 17-NH	15, 16, 18, 19, 23, 24
18	138.8, C
19	114.2, CH	6.52, d (2.0)	23	17, 18, 20, 21, 23
20	129.2, C
21	138.3, C
22	151.0, C
23	113.9, CH	5.98, d (2.0)	19	17, 18, 21, 22
24	168.4, C
25	22.6, CH3	1.70, s		24
1′	93.1, CH	4.45, d (8.0)	2′	9, 2′, 3′, 5′
2′	69.6, CH	2.92, dd (8.0, 3.4)	1′, 3′	1′, 4′
3′	67.5, CH	4.06, dd (8.0, 3.4)	2′, 4′	1′, 5′
4′	69.6, CH	2.98d
5′	75.0, C
4′-NMe2	42.9, CH3	2.79, br s		4′
4′-NMe2	44.4, CH3	2.79, br s		4′
6′-Meα	31.5, CH3	1.43, s		4′, 5′, 6′-Meβ
6′-Meβ	20.6, CH3	1.46, s		4′, 5′, 6′-Meα
13-OH		5.86	13
17-NH		8.41, d (8.0)		16, 17, 24
22-OH		8.45, s		21, 22, 23
2′-OH		4.95, br s	2′
3′-OH		5.73, br s	3′
4′-NH+		9.09, br s	4′-NMe2

^a600 MHz for ¹H NMR and 150 MHz for ¹³C NMR.

^bNumbers of attached protons were determined by analysis of 2D spectra.

^cHMBC correlations are from the stated protons to the indicated carbons.

^dThe coupling constant could not be determined because of overlapping signals.