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. 2009 Nov 30;20(4):763–770. doi: 10.1111/j.1750-3639.2009.00357.x

Figure 1.

Figure 1

Faint (+, A), moderate (++, B) and strong (+++, C) expression of endothelial cell KIT in pediatric pilocytic astrocytomas (original magnification ×200, A; and ×400, B,C). A vascular proliferation with multiple lumens is shown in C. (D) Endothelial cell expression of phosphorylated KIT in pilocytic astrocytoma (+++; ×200). (E) KIT mRNA in endothelial cells (arrowheads) of pilocytic astrocytoma detected by in situ hybridization (×1000). (F) Faint (+) SCF expression in pilocytic astrocytoma (×400). (G) Moderate (++) expression of VEGFR‐2 in astrocytoma tumor cells (×400). (H) Brain endothelial cells showing moderate expression of phosphorylated KIT in a 18‐week‐old fetus (×200, arrows).