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Average percent lesion area (mean ± SD) in innominate artery (A) and aortic sinus (B) in vector control group (VC; n = 5) , wild-type apolipoprotein A-I (apoA-I) gene recipients (A-I; n = 5), and apolipoprotein A-I Milano (apoA-IMilano) gene recipients (A-IM; n = 5) are shown. Mice expressing apoA-IMilano had significantly smaller lesion areas compared with vector control mice and recipients of wild-type apoA-I.
