TABLE 3.
Tissue | Lipid class | Class | SFA | MUFA | PUFA | n3 | n6 | n7 | n9 | Plasmalogen lipids |
---|---|---|---|---|---|---|---|---|---|---|
Plasma | DAG | 0.87 | 0.90 | 0.99 | 0.72 | 0.95 | 0.69 | 0.94 | 0.96 | 0.71 |
Plasma | TAG | 0.71 | 0.73 | 0.61 | 0.77 | 0.84 | 0.75 | 0.59 | 0.62 | 0.67 |
Plasma | FFA | 1.20 | 1.24 | 1.16 | 1.21 | 1.11 | 1.22 | 1.49 | 1.07 | 1.70 |
Plasma | LysoPC | 0.97 | 0.99 | 0.89 | 0.95 | 1.20 | 0.92 | 0.99 | 0.87 | 1.10 |
Plasma | PC | 1.09 | 1.08 | 0.94 | 1.15 | 1.32 | 1.12 | 1.05 | 0.91 | 1.21 |
Plasma | PE | 1.23 | 1.27 | 1.14 | 1.23 | 1.19 | 1.24 | 1.96 | 0.99 | 1.05 |
BAT | DAG | 0.64a | 0.63 | 0.57b | 0.80 | 0.31b | 0.91 | 0.48a | 0.60b | 0.34b |
BAT | TAG | 0.79 | 0.86 | 0.67 | 0.97 | 0.63 | 1.00 | 0.68 | 0.67 | 0.59 |
BAT | FFA | 0.79 | 0.70 | 0.74 | 1.15 | 0.62 | 1.23 | 0.55 | 0.78 | N.D. |
BAT | PC | 1.07 | 1.07 | 0.76 | 0.19 | 1.07 | 1.23 | 0.71 | 0.76 | 0.88 |
Liver | DAG | 0.68 | 0.69 | 0.61 | 0.74 | 0.77 | 0.74 | 0.58 | 0.62 | 0.57 |
Liver | TAG | 0.55b | 0.56b | 0.49b | 0.59b | 0.61b | 0.59b | 0.47b | 0.50 | 0.04 |
Liver | FFA | 1.17 | 1.47b | 0.76a | 1.18 | 1.32 | 1.16 | 0.79 | 0.75 | 4.65 |
Liver | LysoPC | 1.50b | 1.57b | 1.49 | 1.38b | 1.14 | 1.47a | 0.68a | 1.70 | 0.56 |
Liver | PC | 1.12 | 1.13 | 0.94 | 1.17b | 1.37b | 1.11a | 1.09 | 0.91 | 1.16 |
Liver | PE | 1.05 | 1.07 | 0.99 | 1.05 | 1.20 | 0.98 | 1.05 | 0.97 | 1.28b |
Liver | PS | 1.35 | 1.39 | 1.26 | 1.31 | 1.34 | 1.29 | 1.26 | 1.26 | 1.41 |
BAT, brown adipose tissue; DAG, diacylglycerol; N.D., not detectable; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PS, phosphatidylserine; SFA, saturated fatty acid; TAG, triacylglycerol. Values represent the ratio of mean values from Agpat6−/− mice compared with wild-type mice (n = 3 for each) for total lipid class and the fatty acid constituents. Class and ratio of mass for lipid class are indicated; n3, n6, n7, and n9 represent positions of the double bond in the fatty acid chain.
P < 0.08 for Agpat6−/− versus the wild type.
P < 0.05 for Agpat6−/− versus the wild type.