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. Author manuscript; available in PMC: 2010 Jul 10.
Published in final edited form as: J Lipid Res. 2006 Jan 25;47(4):745–754. doi: 10.1194/jlr.M500553-JLR200

TABLE 3.

Effect of Agpat6 deficiency on lipid composition in plasma, BAT, and liver

Tissue Lipid class Class SFA MUFA PUFA n3 n6 n7 n9 Plasmalogen lipids
Plasma DAG 0.87 0.90 0.99 0.72 0.95 0.69 0.94 0.96 0.71
Plasma TAG 0.71 0.73 0.61 0.77 0.84 0.75 0.59 0.62 0.67
Plasma FFA 1.20 1.24 1.16 1.21 1.11 1.22 1.49 1.07 1.70
Plasma LysoPC 0.97 0.99 0.89 0.95 1.20 0.92 0.99 0.87 1.10
Plasma PC 1.09 1.08 0.94 1.15 1.32 1.12 1.05 0.91 1.21
Plasma PE 1.23 1.27 1.14 1.23 1.19 1.24 1.96 0.99 1.05
BAT DAG 0.64a 0.63 0.57b 0.80 0.31b 0.91 0.48a 0.60b 0.34b
BAT TAG 0.79 0.86 0.67 0.97 0.63 1.00 0.68 0.67 0.59
BAT FFA 0.79 0.70 0.74 1.15 0.62 1.23 0.55 0.78 N.D.
BAT PC 1.07 1.07 0.76 0.19 1.07 1.23 0.71 0.76 0.88
Liver DAG 0.68 0.69 0.61 0.74 0.77 0.74 0.58 0.62 0.57
Liver TAG 0.55b 0.56b 0.49b 0.59b 0.61b 0.59b 0.47b 0.50 0.04
Liver FFA 1.17 1.47b 0.76a 1.18 1.32 1.16 0.79 0.75 4.65
Liver LysoPC 1.50b 1.57b 1.49 1.38b 1.14 1.47a 0.68a 1.70 0.56
Liver PC 1.12 1.13 0.94 1.17b 1.37b 1.11a 1.09 0.91 1.16
Liver PE 1.05 1.07 0.99 1.05 1.20 0.98 1.05 0.97 1.28b
Liver PS 1.35 1.39 1.26 1.31 1.34 1.29 1.26 1.26 1.41

BAT, brown adipose tissue; DAG, diacylglycerol; N.D., not detectable; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PS, phosphatidylserine; SFA, saturated fatty acid; TAG, triacylglycerol. Values represent the ratio of mean values from Agpat6−/− mice compared with wild-type mice (n = 3 for each) for total lipid class and the fatty acid constituents. Class and ratio of mass for lipid class are indicated; n3, n6, n7, and n9 represent positions of the double bond in the fatty acid chain.

a

P < 0.08 for Agpat6−/− versus the wild type.

b

P < 0.05 for Agpat6−/− versus the wild type.