Table 2.
Concomitant medications in patients with type 2 diabetes and microalbuminuria at baseline and during follow-up according to treatment with ACE inhibitors YES or NO or with ndCCB YES or NO.
| Baseline | Follow-up | |||||||
|---|---|---|---|---|---|---|---|---|
| ACEi Yes | ACEi No | ndCCB Yes | ndCCB No | ACEi Yes | ACEi No | ndCCB Yes | ndCCB No | |
| Number of patients | 42 | 48 | 50 | 40 | 39 | 44 | 47 | 36 |
|
| ||||||||
| Concomitant medication | number (percent) | number (percent) | ||||||
| Glucose-lowering regimen | ||||||||
| Diet alone | 5 (11.9) | 12 (25.0) | 12 (24.0) | 5 (12.5) | 4 (10.3) | 8 (18.2) | 8 (17.0) | 4 (11.1) |
| Oral hypoglycemic agent alone | 29 (69.0) | 21 (43.8) | 26 (52.0) | 24 (60.0) | 24 (61.5) | 21 (47.7) | 26 (55.3) | 19 (52.8) |
| Insulin and oral hypoglycemic agent | 5 (11.9) | 12 (25.0) | 10 (20.0) | 7 (17.5) | 11 (28.2) | 16 (36.4) | 13 (27.7) | 14 (38.9) |
| Insulin alone | 3 (7.1) | 3 (6.3) | 2 (4.0) | 4 (10.0) | 3 (7.7) | 3 (6.8) | 3 (6.4) | 3 (8.3) |
|
| ||||||||
| Antihypertensive agents | ||||||||
| Any | 22 (52.4) | 26 (54.2) | 23 (46.0) | 25 (62.5) | 32 (82.1) | 38 (86.4) | 37 (78.7) | 33 (91.7) |
| Diuretic | 5 (11.9) | 11 (22.9) | 9 (18.0) | 7 (17.5) | 10 (25.6) | 14 (31.8) | 16 (34.0) | 8 (22.2) |
| Beta-blocker | 6 (14.3) | 2 (4.2) | 3 (6.0) | 5 (12.5) | 4 (10.3) | 3 (6.8) | 4 (8.5) | 3 (8.3) |
| Calcium-channel blocker (dihydropyridine) | 11 (26.2) | 15 (31.3) | 12 (24.0) | 14 (35.0) | 14 (35.9) | 16 (36.4) | 14 (29.8) | 16 (44.4) |
| Sympatholytic agent | 7 (16.7) | 8 (16.7) | 9 (18.0) | 6 (15.0) | 28 (71.8) | 32 (72.7) | 29 (61.7) | 31 (86.1) |
|
| ||||||||
| Lipid-lowering agents | ||||||||
| Any | 3 (7.1) | 3 (6.3) | 1 (2.0) | 5 (12.5) | 6 (15.4) | 9 (20.5) | 6 (12.8) | 9 (25.0) |
| Statin alone | 0 | 1 (2.1) | 0 | 1 (2.5) | 2 (5.1) | 7 (15.9) | 4 (8.5) | 5 (13.9) |
| Fibrate alone | 3 (7.1) | 1 (2.1) | 0 | 4 (10.0)* | 2 (5.1) | 0 | 1 (2.1) | 1 (2.8) |
| Statin and fibrate | 0 | 0 | 0 | 0 | 2 (5.1) | 1 (2.3) | 0 | 3 (8.3) |
|
| ||||||||
| Antiplatelet agent | 1 (2.4) | 0 | 1 (2.0) | 0 | 6 (15.4) | 3 (6.8) | 6 (12.8) | 3 (8.3) |
*P < .05 versus ndCCB YES.