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. Author manuscript; available in PMC: 2010 Jul 11.
Published in final edited form as: Physiol Rev. 2007 Apr;87(2):593–658. doi: 10.1152/physrev.00035.2006

FIG. 9.

FIG. 9

Biphasic Hill equation fits to InsP3R channel Po versus [Ca2+]i data. Open squares are experimental data, and smooth curves are Hill equation fit to the data using parameters as tabulated. A: channel Po data for recombinant rat type 1 E2100D mutant InsP3R expressed in Sf9 cells were fitted (black curve) using modified biphasic Hill equation (Eq. 2) with parameters given in Ref. 479, tabulated in black. An alternative Hill equation fit (thick yellow curve) using the same equation with a different set of parameters (tabulated in yellow) is effectively indistinguishable from the fit provided in Ref. 479. B: channel Po data for recombinant wild-type Drosophila InsP3R channel expressed in Sf9 cells were fitted (black curve) using modified biphasic Hill equation (Eq. 2) with parameters given in Ref. 434, tabulated in black. The more general Hill equation (Eq. 1) gives a better fit to the data (red curve) using parameters tabulated in red.