Fig. 1.

Genome organization and domain structure of the calflagins. (A) The calflagin genes are organized in a tandem array (black rectangles) in a 7.6-kb region of chromosome 8. Calflagins Tb44, Tb24, and Tb17 are offset from an additional copy of Tb24 by another gene encoding a putative amino acid transporter (open rectangle). (B) Calflagins Tb24 and Tb17 each have EF-hand domains (closed rectangles). Calflagin Tb17 also contains a 15-amino-acid extension at the C terminus relative to Tb24 (gray). Calflagin Tb44 has a duplication of a 186-amino-acid Tb24/Tb17 core sequence, separated by a short 8-amino-acid hinge peptide (gray).