Table 3.
Documented conditions associated with low SVR
| Condition | Comment |
| Sepsis | Most common cause of low SVR |
| Pancreatitis | Seen with necrotizing or hemorrhagic |
| pancreatitis | |
| Cirrhosis | Seen with decompensated liver disease |
| Adrenal insufficiency | Only 15 well documented cases |
| Head injury | Seen after initial rise in SVR |
| Beriberi | Rapid response to thiamine |
| Salicylate (chronic) | Seen in elderly patients, illness mimics sepsis |
| TMP-SMX | Reported only in AIDS patients |
| Vasoplegic syndrome | Occurs within 6 h postcardiopulmonary |
| bypass | |
| Incidence estimated to be 0.4%-5.0% |
SVR, systemic vascular resistance (dynes × s/cm5); TMP-SMX, trimethoprim-sulfamethoxazole. See text for discussion.