Figure 5.
Measured EPSC amplitude correlates with model predictions. The abscissa indicates the amplitude of each cell’s EPSP as fitted by the model (Vepsp, from Table 1). The ordinate indicates the EPSC size estimated from the initial slope of the synaptic potentials measured extracellularly, which is an estimate of EPSC amplitude. To control for variations across cells in electrode impedance and distance from the soma, we corrected these measures by dividing by the amplitude of the extracellularly measured spike. Slope measurements were taken for ~4000 synaptic potentials. Error bars are ±1 s.d. The regression was performed through robust fitting, which gave a small weight to the outlier. There is a positive and significant (p = 0.014) correlation across cells between the measured EPSC and the EPSP size predicted by the model.