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. 2010 Jun 9;8(6):1817–1837. doi: 10.3390/md8061817

Table 1.

Inhibition of serine proteases by peptides from the cyanobacterial genus Lyngbya (IC50, μM).

Name Elastase Chymotrypsin Trypsin Reference
Tiglicamide A (44) 2.14 >50 >50 [38]
Tiglicamide B (45) 6.99 >50 >50 [38]
Tiglicamide C (46) 7.28 >50 >50 [38]
Largamide A (47) 1.41 >50 >50 [39]
Largamide B (48) 0.53 >50 >50 [39]
Largamide C (49) 1.15 >50 >50 [39]
Pompanopeptin A (55) 2.4 [42]
Lyngbyastatin 4 (59) 0.0139 or 0.03 4.3 or 0.3 >30 [44,45]
Lyngbyastatin 5 (60) 0.0032 2.8 >30 [45]
Lyngbyastatin 6 (61) 0.0033 2.5 >30 [45]
Lyngbyastatin 8 (62) 0.0083 or 0.047 2.5 >30 [45,46]
Lyngbyastatin 9 (63) 0.123 / / [46]
Lyngbyastatin 10 (64) 0.210 / / [46]
Lyngbyastatin 7 (65) 0.120 / / [46]
Somamide B (66) 0.0095 4.2 >30 [47]
Kempopeptin A (67) 0.32 2.6 >67 [48]
Kempopeptin B (68) >67 >67 8.4 [48]
Scyptolin A (69) 2.8 / >446 [50]