Skip to main content
. Author manuscript; available in PMC: 2010 Jul 12.
Published in final edited form as: Gene. 2006 Feb 20;372:103–109. doi: 10.1016/j.gene.2005.12.013

Fig. 5.

Fig. 5

Effects of PGE2 and LTB4 on MMP-3 mRNA expression and protein production. A. A representative RT-PCR result from three independent experiments using cells from two different donors. B. The combined densitometric data from three independent experiments. The data show that MMP-3 mRNA level was markedly increased by PGE2 compared to the control while it was reduced by LTB4 compared to the control. A pretreatment with LTB4 for 30 min prior to PGE2 treatment brought the levels back to the control level. C. MMP-3 protein production also increased by PGE2 treatment and decreased by LTB4, while combined treatment brought the levels close to the control. Two independent experiments were performed with a total sample size of 6.