Table II.
Relative risk (RR) with 95 percent confidence interval (CI) for cancer of the colon and rectum among women by sub site and by estimated physical activity in 1960 and 1970. Results obtained by Poisson regression.
| Anatomic subsite (ICDO-7) | Occupational PA | Census 1960 | Census 1970 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases | RRa | 95 % CI | RRb | 95 % CI | Cases | RRa | 95 % CI | RRb | 95 % CI | ||
| Colon (153) | Very high/high | 1073 | 1.0 | Ref. | 1.0 | Ref. | 1442 | 1.0 | Ref. | 1.0 | Ref. |
| Moderate | 1759 | 1.0 | 0.9–1.1 | 1.0 | 0.9–1.1 | 1812 | 1.0 | 1.0–1.1 | 1.1 | 1.0–1.1 | |
| Light | 1876 | 1.1 | 1.0–1.1 | 1.1 | 1.0–1.2 | 1372 | 1.1 | 1.0–1.1 | 1.1 | 1.0–1.2 | |
| Sedentary | 1033 | 1.1 | 1.0–1.2 | 1.1 | 1.1–1.3 | 732 | 1.1 | 1.0–1.2 | 1.2 | 1.1–1.4 | |
| p=0.014 | p=0.0055 | p=0.10 | p<0.001 | ||||||||
| Proximal (153.0–.1) | Very high/high | 510 | 1.0 | Ref. | 1.0 | Ref. | 663 | 1.0 | Ref. | 1.0 | Ref. |
| Moderate | 850 | 1.0 | 0.9–1.1 | 1.1 | 0.9–1.2 | 810 | 1.0 | 0.9–1.1 | 1.0 | 0.9–1.1 | |
| Light | 884 | 1.1 | 0.9–1.2 | 1.1 | 1.0–1.2 | 606 | 1.0 | 0.9–1.1 | 1.1 | 1.0–1.2 | |
| Sedentary | 497 | 1.2 | 1.0–1.3 | 1.2 | 1.0–1.5 | 344 | 1.2 | 1.0–1.3 | 1.2 | 1.0–1.5 | |
| p=0.024 | p=0.011 | p=0.056 | p=0.0032 | ||||||||
| Ascending + Cecum (153.0) | Very high/high | 357 | 1.0 | Ref. | 1.0 | Ref. | 489 | 1.0 | Ref. | 1.0 | Ref. |
| Moderate | 633 | 1.1 | 1.0–1.2 | 1.1 | 1.0–1.3 | 594 | 1.0 | 0.9–1.1 | 1.0 | 0.9–1.2 | |
| Light | 635 | 1.1 | 1.0–1.2 | 1.1 | 1.0–1.3 | 425 | 1.0 | 0.9–1.1 | 1.0 | 0.9–1.2 | |
| Sedentary | 350 | 1.2 | 1.0–1.4 | 1.3 | 1.0–1.6 | 238 | 1.1 | 0.9–1.3 | 1.2 | 0.9–1.4 | |
| p=0.062 | p=0.0084 | p=ns | p=0.096 | ||||||||
| Transverse+Flexures (153.1) | Very high/high | 153 | 1.0 | Ref. | 1.0 | Ref. | 174 | 1.0 | Ref. | 1.0 | Ref. |
| Moderate | 217 | 0.9 | 0.7–1.1 | 0.9 | 0.7–1.1 | 216 | 1.0 | 0.8–1.3 | 1.0 | 0.8–1.3 | |
| Light | 249 | 1.0 | 0.8–1.2 | 1.0 | 0.8–1.3 | 181 | 1.2 | 0.9–1.4 | 1.3 | 1.0–1.6 | |
| Sedentary | 147 | 1.1 | 0.9–1.4 | 1.1 | 0.8–1.5 | 106 | 1.3 | 1.0–1.7 | 1.5 | 1.1–2.2 | |
| p=ns | p=ns | p=0.013 | p=0.0037 | ||||||||
| Distal (153.2–.3) | Very high/high | 410 | 1.0 | Ref. | 1.0 | Ref | 563 | 1.0 | Ref. | 1.0 | Ref. |
| Moderate | 641 | 1.0 | 0.8–1.1 | 1.0 | 0.9–1.1 | 722 | 1.1 | 0.9–1.2 | 1.1 | 1.0–1.2 | |
| Light | 714 | 1.0 | 0.9–1.2 | 1.1 | 0.9–1.2 | 526 | 1.0 | 0.9–1.2 | 1.1 | 1.0–1.3 | |
| Sedentary | 383 | 1.0 | 0.9–1.2 | 1.2 | 1.0–1.4 | 272 | 1.0 | 0.9–1.2 | 1.1 | 0.9–1.4 | |
| p=ns | p=0.022 | p=ns | p=0.045 | ||||||||
| Descending (153.2) | Very high/high | 66 | 1.0 | Ref. | 1.0 | Ref. | 80 | 1.0 | Ref. | 1.0 | Ref. |
| Moderate | 80 | 0.7 | 0.5–1.0 | 0.7 | 0.5–1.0 | 103 | 1.1 | 0.8–1.4 | 1.0 | 0.7–1.4 | |
| Light | 108 | 1.0 | 0.7–1.3 | 1.0 | 0.7–1.4 | 73 | 1.0 | 0.7–1.4 | 0.9 | 0.6–1.3 | |
| Sedentary | 53 | 0.9 | 0.6–1.3 | 1.0 | 0.6–1.7 | 41 | 1.1 | 0.7–1.6 | 1.0 | 0.6–1.7 | |
| p=ns | p=ns | p=ns | p=ns | ||||||||
| Sigmoid (153.3) | Very high/high | 344 | 1.0 | Ref. | 1.0 | Ref. | 483 | 1.0 | Ref. | 1.0 | Ref. |
| Moderate | 561 | 1.0 | 0.9–1.1 | 1.0 | 0.9–1.2 | 619 | 1.1 | 0.9–1.2 | 1.1 | 1.0–1.2 | |
| Light | 606 | 1.1 | 0.9–1.2 | 1.1 | 1.0–1.3 | 453 | 1.0 | 0.9–1.2 | 1.1 | 1.0–1.3 | |
| Sedentary | 330 | 1.1 | 0.9–1.3 | 1.2 | 1.0–1.5 | 231 | 1.0 | 0.9–1.2 | 1.2 | 0.9–1.4 | |
| p=ns | p=0.039 | p=ns | p=0.070 | ||||||||
| Rectum (154) | Very high/high | 539 | 1.0 | Ref. | 1.0 | Ref. | 778 | 1.0 | Ref. | 1.0 | Ref. |
| Moderate | 937 | 1.1 | 1.0–1.2 | 1.1 | 1.0–1.2 | 1012 | 1.1 | 1.0–1.2 | 1.1 | 1.0–1.2 | |
| Light | 986 | 1.1 | 1.0–1.2 | 1.1 | 1.0–1.3 | 768 | 1.1 | 1.0–1.2 | 1.1 | 1.0–1.2 | |
| Sedentary | 526 | 1.1 | 0.9–1.2 | 1.1 | 0.9–1.3 | 403 | 1.1 | 1.0–1.2 | 1.0 | 0.9–1.2 | |
| p=ns | p=ns | p=ns | p=ns | ||||||||
a
Relative risk adjusted for age by 5 years interval, and calendar year of follow-up by year.
b
Relative risk adjusted for age by 5 years interval, calendar year of follow-up by year, place of residence and socioeconomic status.