Numerical simulations superimposed on data for the entire set of data for 60 min of anoxia in EDL (A and B) and 46 min of anoxia in SOL (C and D) These data are included in the means for all of the experiments displayed in Fig. 1. A, the EDL muscles were normoxic for 20 min, then anoxic for the next 60 min and restored to normoxia after 80 min. Lines are the simulation results for the entire time course of the experimental measurements; the continuous line, PCr; the dashed line, Pi; dotted line, ATP. Filled circles are the mean data for PCr with one s.d. The open circles are the mean data for Pi with one s.d. B, pH data from experiment shown in A. Continuous line is the simulation of pH for the entire time course of the experimental measurements. Filled squares are the mean data for pH with one s.d. C, the SOL muscles were normoxic for 20 min, then anoxic for the next 46 min and restored to normoxic after 66 min. Lines are the simulation results for the entire time course of the experimental measurements; the continuous line, PCr; the dashed line, Pi; dotted line, ATP. Filled circles are the mean data for PCr with one standard deviation. The open circles are the averaged data for Pi with one s.d. D, pH data from experiment shown in C. Continuous line is the simulation of pH for the entire time course of the experimental measurements. Filled squares are the averaged data for pH with one s.d.