. Author manuscript; available in PMC: 2011 Feb 1.

Published in final edited form as: Arch Neurol. 2010 Feb;67(2):171–177. doi: 10.1001/archneurol.2010.113

Table 2.

Summary of demographics and clinical data grouped by generation

	Generation GII	Generation GIII

Number of Affected Individuals	5	3

Mean Age of Onset (yrs)	75.8	60.7
Range	69-80	55-66

Duration (yrs)	5.8	> 5
Range	2 - 7	> 5 - 10

Clinical Manifestations	3 Alzheimer's Disease	Primary Progressive Aphasia
	1 FTD	FTD/DLB features
	1 Dementia NOS	MCI

Autopsy findings	FTLD-U + NII	FTLD-U + NII

Abbreviations: FTD=frontotemporal dementia; FTLD-U + NII=frontotemporal lobar degeneration with ubiquitin positive neuronal cytoplasmic and intranuclear inclusions; LBD=Lewy body disease; MCI=mild cognitive impairment; NOS=not otherwise specified