Table 2.
Demographics and clinical measurements of drug free patients with paranoid schizophrenia compared with control subjects which were closely matched for BMI and smoking habits. Annotation: data are given as mean ± standard deviation (SD), n.a. = not applicable, aANOVA, bChi-square-test, ↑↓ positive or negative influence on measures, bold P-values were significant.
Demographic data | Controls (n = 11) | Paranoid schizophrenia: drug free (n = 11) | Schizophrenia versus controls P-values |
---|---|---|---|
Age [y] | 34.7 ± 12.0 | 35.1 ± 13.2 | 0.947a |
Duration of disease [y] | — | 8.5 ± 10.8 | — |
Male/Female [n] | 7/4 | 7/4 | 1.000b |
BMI [kg/m2] | 23.5 ± 3.4 | 24.5 ± 5.5 | 0.621a |
Smokers/non-smokers [n] | 6/5 | 7/4 | 0.665b |
| |||
Measures | Mean ± SD | Mean ± SD | |
S100B [μg/L] | 0.046 ± 0.014 | 0.073 ± 0.033 | 0.028a↑ |
| |||
hs-CRP [mg/L] | 1.47 ± 1.64 | 2.50 ± 2.51 | 0.267a |
TNF-α [ng/L] | 2.51 ± 1.95 | 2.95 ± 1.79 | 0.584a |
Leptin [μg/L] | 11.82 ± 16.91 | 13.74 ± 12.49 | 0.766a |
MCP-1 [ng/L] | 314.9 ± 190.0 | 308.8 ± 166.2 | 0.936a |
HGF [μg/L] | 2.32 ± 1.85 | 2.84 ± 2.11 | 0.543a |
Resistin [μg/L] | 5.71 ± 1.80 | 6.70 ± 1.83 | 0.214a |
PAI-1 [μg/L] | 1.49 ± 0.75 | 2.30 ± 1.55 | 0.139a |
| |||
Triglycerides [mg/dL] | 144.3 ± 47.2 | 205.6 ± 102.3 | 0.093a↑ |
Glucose [mg/dL] | 81.1 ± 12.2 | 105.7 ± 25.0 | 0.011a↑ |
C-peptide [pmol/L] | 1219.0 ± 680.1 | 2760.3 ± 1657.0 | 0.013a↑ |