Table 1.
Reclassification of Subjects into Prognostic Groups by Adding Two Biomarkers, BNP and hs-TnT, to a Prediction Model Based on Other Baseline Assessments.
| Model 1: Baseline Assessments | Model 2: Baseline Assessments + Biomarkers | ||
|---|---|---|---|
| Predicted Probability <10% | Predicted Probability ≥10% | Total | |
| Predicted Probability <10% | |||
| Number of subjects | 2003 (85%)* | 342 (15%) | 2345 |
| Observed Dead | 4.4% | 12.3% | 5.6% |
| Predicted Dead Model 1 | 5.7% | 7.8% | 6.0% |
|
| |||
| Predicted Probability ≥10% | |||
| Number of subjects | 345 (29%) | 861(71%) | 1206 |
| Observed Dead | 7.2% | 20.3% | 16.6% |
| Predicted Dead Model 1 | 13.0% | 16.9% | 15.8% |
|
| |||
| Total | |||
| Number of subjects | 2348 (66%) | 1203 (34%) | 3551 |
| Observed Dead | 4.9% | 18.0% | 9.3% |
| Predicted Dead Model 2 | 5.0% | 17.8% | |
*Percentages in parentheses are calculated across each row.