Table 1.
Baseline clinical and laboratory features of 12 children with hypoparathyroidism at study entry
| Patient no. | Age (yr) | Sex | Calcium (mmol/liter) (2.05–2.5) | Phosphorus (mmol/liter) (0.8–1.6) | Magnesium (mmol/liter) (0.65–1.05) | Alkaline phosphatase (U/liter) (100–320) | Urinary calcium (mmol per 24 h) (1.25–6.25) | Urinary phosphorus (13–42 mmol per 24 h) | Urinary magnesium (3–4.3 mmol per 24 h) | Corrected creatinine clearance (80–130 ml/min per 1.73 m2) |
|---|---|---|---|---|---|---|---|---|---|---|
| PTH | ||||||||||
| 1 | 10 | M | 1.84 | 1.96 | 0.71 | 461 | 5.25 | 26.0 | 5.22 | 148 |
| 2 | 7 | F | 1.86 | 2.33 | 0.53 | 207 | 4.61 | 15.8 | 4.78 | 71 |
| 3 | 8 | M | 1.93 | 2.51 | 0.70 | 300 | 1.86 | 13.7 | 2.09 | 80 |
| 4 | 12 | F | 2.16 | 2.09 | 0.77 | 178 | 7.11 | 28.3 | 5.61 | 141 |
| 5 | 12 | M | 2.04 | 2.50 | 0.66 | 550 | 4.08 | 27.8 | 6.00 | 94 |
| 6 | 14 | M | 1.68 | 2.41 | 0.65 | 287 | 6.07 | 20.0 | 5.34 | 119 |
| 7 | 10 | M | 1.70 | 2.09 | 0.62 | 248 | 8.87 | 20.3 | 6.96 | 86 |
| Mean ± sd | 10.2 ± 2.3 | 60% M | 1.89 ± 0.18 | 2.27 ± 0.22 | 0.66 ± 0.08 | 319 ± 137 | 5.41 ± 2.25 | 21.7 ± 5.8 | 5.14 ± 1.51 | 106 ± 31 |
| Calcitriol | ||||||||||
| 8 | 6 | M | 1.84 | 2.60 | 0.76 | 231 | 2.25 | 13.7 | 2.80 | 155 |
| 9 | 12 | F | 1.84 | 2.26 | 0.58 | 422 | 5.70 | 43.3 | 6.41 | 64 |
| 10 | 11 | M | 2.04 | 2.41 | 0.78 | 295 | 8.60 | 33.5 | 7.11 | 99 |
| 11 | 10 | M | 1.81 | 2.34 | 0.74 | 362 | 4.93 | 22.5 | 3.18 | 167 |
| 12 | 5 | F | 2.06 | 2.06 | 0.68 | 246 | 3.67 | 12.3 | 4.38 | 72 |
| Mean ± sd | 8.8 ± 2.9 | 71% M | 1.92 ± 0.12 | 2.33 ± 0.20 | 0.71 ± 0.08 | 311 ± 80 | 5.03 ± 2.39 | 25.1 ± 13.2 | 4.78 ± 1.92 | 111 ± 47 |
M, Male, F, female.