Skip to main content
. Author manuscript; available in PMC: 2010 Jul 12.
Published in final edited form as: J Neuroimmunol. 2010 Mar 5;221(1-2):46–52. doi: 10.1016/j.jneuroim.2010.02.011

Fig. 5.

Fig. 5

C5aR inhibition reduces apoptosis in lupus brain. DNA was isolated from brains and subjected to LM-PCR to assess apoptotic DNA laddering. Significant apoptosis was observed in the brains of the MRL/lpr mice, which was considerably reduced by C5aR inhibition. Given are representative samples from the saline-treated and C5aRa-treated MRL/lpr groups. Each lane contains brain tissue harvested from an individual animal.