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. Author manuscript; available in PMC: 2010 Jul 12.
Published in final edited form as: J Neuroimmunol. 2010 Mar 5;221(1-2):46–52. doi: 10.1016/j.jneuroim.2010.02.011

Fig. 6.

Fig. 6

C5a/C5aR signaling regulates the expression of signaling proteins in lupus brain. The expression of survival factors p-Akt and other signaling molecules, p-Erk, p-JNK, p-STAT1 was assessed by western blotting with equal amounts of protein. They were normalized to the housekeeping protein, actin. The expression of p-Akt was significantly reduced while all the other molecules were up-regulated in MRL/lpr brain. The alteration in expression was alleviated by C5aR inhibition. All changes of *p<0.05 were considered significant. Shown are representative blots from three separate experiments.