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. 2010 Jun 2;11(2):976–985. doi: 10.1208/s12249-010-9451-7

Table V.

Composition of Checkpoint Formulations, the Predicted and Experimental Values of Response Variables and Percentage Prediction Error

Optimized formulation composition (X 1/X 2/X 3) Response variable Experimental value Predicted value Percentage prediction error
0.251:6.05:8.2 Y 1 8,275.1 8,409.5 −1.62
Y 2 98.4 101.4 −3.06
Y 3 0.27 0.29 −7.25
0.751:8.85:7.6 Y 1 7,840.3 7,736.1 1.33
Y 2 92.1 91.2 0.97
Y 3 0.25 0.22 9.94
0.73:8.23:7.4 Y 1 7,794.6 7,965.9 −2.20
Y 2 92.8 94.4 −1.79
Y 3 0.21 0.24 −12.35
0.79:5.75:11.1 Y 1 8,436.1 8,516.9 −0.96
Y 2 100.5 102.1 −1.57
Y 3 0.36 0.33 7.23
0.93:5.3:13.4 Y 1 7,720.8 7,747.1 −0.34
Y 2 92.4 91.3 1.17
Y 3 0.42 0.41 2.34
0.5:5.85:8.3 Y 1 8,725.3 8,836.6 −1.28
Y 2 104.6 106.9 −2.29
Y 3 0.31 0.32 −4.72
0.88:7.1:9.8 Y 1 8,310.5 8,280.6 0.36
Y 2 97.1 98.7 −1.63
Y 3 0.23 0.25 −9.17