Table X.

Response Values at High and Low Level of Individual Factor at Middle Level of Remaining Factors

Sr. No.	Factor	Code	Level	Response Value at middle level of other factors
				Y 1	Y 2	Y 3	Y 4
1	Poly (ethylene oxide)	X 1	Low	5.5	0.41	83.71	94.44
	molecular weight	X 1	High	6.05	0.39	81.84	92.44
2	Poly (ethylene oxide)	X 2	Low	3.9	0.22	91.9	97.31
	amount (mg)	X 2	High	7.65	0.58	73.65	89.57
3	Ethylcellulose	X 1	Low	3.87	0.25	91.65	97.71
	amount (mg)	X 1	High	7.68	0.56	73.9	89.16
4	Drug solubility	X 2	Low	7.03	0.50	78.5	90.02
	(mg/mL)	X 2	High	4.52	0.32	87.04	96.86
5	Drug amount (mg)	X 1	Low	5.53	0.45	83.3	94.21
		X 1	High	6.01	0.36	82.25	92.67
6	Sodium chloride	X 2	Low	5.08	0.35	86.11	95.31
	amount (mg)	X 2	High	6.46	0.45	79.43	91.57
7	Citric acid amount	X 1	Low	6.45	0.46	79.52	91.69
	(mg)	X 1	High	5.1	0.34	86.02	95.18
8	Polyethylene glycol	X 2	Low	4.87	0.41	85.78	96.08
	amount (mg)	X 2	High	6.68	0.39	79.77	90.8
9	Glycerin amount	X 2	Low	6.7	0.46	78.07	91.35
	(mg)	X 2	High	4.85	0.34	87.48	95.52

X ₁–Poly (ethylene oxide) molecular weight

X ₂–Poly (ethylene oxide) amount