Fig. 2.

Dissolution profiles of IM from melt extrusion system and wet extrusion system of IM and HP-β-CyD (equivalent to 50 mg of IM) in pH 6.8 phosphate buffer at 37°C. Unfilled circles IM alone, filled circles physical mixture, unfilled triangles extrudate containing IM and HP-β-CyD manufactured by melt extrusion, unfilled triangles extrudate containing IM and HP-β-CyD manufactured by wet extrusion. Each point represents the mean ± SD of three experiments