Table II.
Physical Evaluation of Trial Formulations
Physical evaluation of trial formulations | |||||||||
---|---|---|---|---|---|---|---|---|---|
F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | |
Angle of repose (n = 3) | 28.96 ± 1.78 | 26.97 ± 2.56 | 23.45 ± 1.15 | 27.13 ± 2.12 | 25.89 ± 2.35 | 26.76 ± 2.53 | 23.56 ± 1.22 | 24.54 ± 2.32 | 26.49 ± 3.08 |
% Carr’s Index (n = 3) | 4.444 ± 1.45 | 7.317 ± 2.22 | 5.128 ± 1.34 | 2.778 ± 2.15 | 4.651 ± 1.33 | 4.762 ± 2.92 | 5.714 ± 1.65 | 2.500 ± 2.52 | 2.326 ± 2.16 |
Mean weight in mg (n = 20) | 359.52 ± 15.22 | 340.32 ± 16.45 | 329.23 ± 13.22 | 331.54 ± 16.209 | 350.52 ± 16.78 | 342.54 ± 15.76 | 325.22 ± 14.23 | 350.82 ± 13.28 | 360.47 ± 12.65 |
Thickness in mm (n = 20) | 2.34 ± 0.054 | 2.21 ± 0.098 | 2.08 ± 0.103 | 2.14 ± 0.063 | 2.28 ± 0.012 | 2.22 ± 0.013 | 2.06 ± 0.123 | 2.31 ± 1.44 | 2.37 ± 1.057 |
Diameter in mm (n = 20) | 12.34 ± 0.021 | 12.12 ± 0.023 | 12.25 ± 0.015 | 12.31 ± 0.018 | 12.41 ± 0.107 | 12.35 ± 1.02 | 12.22 ± 0.015 | 12.37 ± 0.022 | 12.33 ± 0.019 |
Hardness in kg (n = 20) | 12.54 ± 4.45 | 10.99 ± 3.62 | 10.68 ± 4.52 | 12.32 ± 5 | 12.55 ± 2.52 | 12.35 ± 5.54 | 11.55 ± 3.56 | 12.45 ± 4.25 | 12.49 ± 3.25 |
Friability in % (n = 10) | 0.12 | 0.4 | 0.25 | 0.12 | 0.15 | 0.12 | 0.11 | 0.1 | 0.12 |
Content uniformity in % (n = 20) | 89.55 | 92.68 | 95.58 | 90.69 | 87.98 | 88.78 | 91.08 | 88.82 | 87.56 |