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. 2010 Apr 27;11(2):708–718. doi: 10.1208/s12249-010-9427-7

Table III.

Release Kinetics of Famotidine F1–F9 Formulations

Zero order First order Higuchi Korsmeyer–Peppas Hixson–Crowell Baker and Lonsdale Weibull model MDT
r 2 K 0(h −1) r 2 K 1(h −1) r 2 k H(h −½) r 2 n K kp(h n) r 2 K HC(h −1/3) r 2 K B&L r 2 β α h
F1 0.859 17.68 0.951 0.561 0.925 59.75 0.941 0.74 0.094 0.953 0.903 0.939 0.127 0.938 1.439 1.739 1.469
F2 0.855 9.204 0.959 0.214 0.925 36.98 0.944 0.745 0.093 0.981 0.392 0.979 0.051 0.994 1.399 4.7 3.027
F3 0.909 5.963 0.855 0.128 0.974 30.36 0.945 0.725 0.099 0.974 0.206 0.981 0.024 0.976 1.215 7.901 5.481
F4 0.984 3.217 0.875 0.042 0.985 19.58 0.976 0.572 0.156 0.949 0.099 0.878 0.012 0.943 0.848 7.175 10.215
F5 0.978 3.184 0.898 0.034 0.981 19.42 0.978 0.691 0.085 0.952 0.088 0.864 0.009 0.968 0.924 9.143 10.969
F6 0.976 3.208 0.886 0.038 0.988 19.64 0.992 0.639 0.103 0.951 0.093 0.872 0.1 0.968 0.889 8.09 10.509
F7 0.971 3.163 0.796 0.058 0.983 19.37 0.973 0.521 0.153 0.926 0.116 0.879 0.015 0.913 0.848 6.617 9.285
F8 0.931 2.89 0.977 0.023 0.984 18.09 0.905 0.957 0.036 0.971 0.067 0.958 0.006 0.905 1.064 11.37 9.827
F9 0.933 2.744 0.977 0.02 0.986 17.18 0.928 0.992 0.030 0.969 0.06 0.913 0.005 0.958 1.156 14.17 9.910