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. 2010 May 5;11(2):786–792. doi: 10.1208/s12249-010-9441-9

Table I.

Particle Size of Gliclazide Microcrystals Prepared by Solvent-Change and pH-Shift Methods, and Untreated Drug

Formulation Particle size (μm) Span
Untreated drug 290.00 ± 36.05 2.10 ± 0.20
D0.5B0.05 9.90 ± 0.26 1.24 ± 0.02
D0.3B0.05 4.76 ± 0.15 1.52 ± 0.02