Table II.
Pharmacokinetic Parameters | MM1 | SE1 | Pure drug |
---|---|---|---|
t max (hr) | 1 | 0.5 | 0.5 |
C max (ng/ml) | 2,462.2 | 20,221.37 | 1,354.8 |
AUC0-t (ng/ml h) | 5,379.286 | 12,649.9 | 2,064.45 |
AUC0-∞ (ng/ml h) | 5,403.56 | 12,688.12 | 2,071.96 |
K el (h−1) | 0.495 | 0.407 | 0.301 |
t 1/2 (h) | 1.4 | 1.7 | 2.3 |