Relationship between measured quantities for the QC and ACI configurations. ACI Andersen 8-stage cascade impactor, APSD Aerodynamic particle size distribution, AUC Area Under the Curve of APSD, ISM Impactor sized mass, i.e., mass entering the impactor excluding non-sizing portions, LPM Large particle mass, MMAD Mass median aerodynamic diameter, QC Quality control, abbreviated impactor for orally inhaled drug product quality control, SPM Small particle mass