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. 2010 Jul 12;5(7):e11548. doi: 10.1371/journal.pone.0011548

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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HAI antibody in ferrets (n = 4 per group) vaccinated with either 30 µg or 7.5 µg of influenza H1N1 HA1 or HA. Blood was collected at day 35 (post-dose 2). HAI responses were assessed against A/California/07/2009. Bars indicate geometric mean titer (GMT). The titer from each individual ferret is indicated by symbol. *p = 0.05 HA (1–480) low dose vs. HA (1–480) high dose.