Table 2. Mean reciprocal neutralizing titers of Rabbit and Sheep anti-HA sera.
RABBIT | SERA | END-POINT TITERS* |
H1N1-HA (1–330) | Pre Vaccine | <20 |
Post- 1 | 40 | |
Post- 2 | 6,400 | |
Post- 3 | 25,600 | |
H1N1-HA (1–480) | Pre Vaccine | <20 |
Post- 1 | <20 | |
Post- 2 | 3,200 | |
Post- 3 | 6,400 | |
SHEEP | ||
Mammalian H1N1-HA0 | Pre Vaccine | <20 |
Post- 1 | <20 | |
Post- 2 | 1,600 | |
Post- 3 | 6,400 | |
H1N1-HA (1–330) | Pre Vaccine | <20 |
Post- 1 | 80 | |
Post- 2 | 12,800 | |
Post- 3 | 51,200 |
*End-point titers (mean of three replicates) using polyclonal rabbit sera in a microneutralization assay performed with A/California/07/2009 (X-179A).